Oxidant-Antioxidant Balance in the Blood of Patients with Chronic Obstructive Pulmonary Disease After Smoking Cessation

Table 3

Levels of lipid peroxidation products in the COPD patients who had given up smoking and in the representatives of the control groups: COPD patients who had not given up smoking and healthy subjects.

Group	Parameters
	CDplasma; (10^−2 Abs./mL)	CDeryth.; (10^−1 Abs./g Hb)	TBARSplasma; (10^−1 nmol MDA/mL)	TBARSeryth.; (nmol MDA/g Hb)
Control I (healthy nonsmokers)	4.1 ± 1.5	1.4 ± 0.2	2.8 ± 0.3	25.0 ± 6.5
COPD patients who had not given up smoking (Control II)
At the beginning of the study	13.8 ± 5.8***	9.5 ± 3.3***	5.1 ± 1.5***	37.1 ± 17.9**
After the 1st month of the study	14.5 ± 5.5***	9.7 ± 2.7***	5.2 ± 1.5***	37.7 ± 15.1**
After the 2nd month of the study	14.9 ± 3.9***	11.0 ± 4.7***	5.3 ± 1.5***	37.5 ± 11.6**
After the 3rd month of the study	14.9 ± 3.5***	10.9 ± 2.8***	5.7 ± 1.6***	37.3 ± 12.9**
COPD patients who had given up smoking (study group)
Before smoking cessation	13.5 ± 5.8***	9.3 ± 4.3***	5.3 ± 1.8***	37.8 ± 17.3**
After the 1st month of tobacco; abstinence	13.4 ± 5.4***	6.2±1.7^∗∗∗aaabbbcccdddeee	5.3 ± 1.7***	38.1 ± 16.2**
After the 2nd month of tobacco; abstinence	11.8 ± 3.3***	4.6±2.2^∗∗∗aaabbbcccdddeee	4.9 ± 1.5***	33.0 ± 11.4
After the 3rd month of tobacco; abstinence	7.3 ± 2.6^aaabbbcccdddeeefffggg	2.7 ± 1.1^aaabbbcccdddeeefffg	3.1 ± 0.7^aaabbbcccdddeeefffggg	26.1 ± 9.3^abcdeeff

COPD: chronic obstructive pulmonary disease; CDs: conjugated dienes; TBARS: thiobarbituric acid-reactive substances.
Data expressed as mean 𝑥±SD.
Statistically significant differences versus Control I: **P < 0.01, ***P < 0.001; versus Control II at the beginning of the study: ^aP < 0.05, ^aaaP < 0.001; versus Control II after the 1st month: ^bP < 0.05, ^bbbP < 0.001; versus Control II after the 2nd month: ^cP < 0.05, ^cccP < 0.001; versus Control II after the 3rd month: ^dP < 0.05, ^dddP < 0.001; versus the study group before smoking cessation: ^eeP < 0.01, ^eeeP < 0.001; versus the study group after the 1st month of tobacco abstinence: ^ffP < 0.01, ^fffP < 0.001; versus the study group after the 2nd month of tobacco abstinence: ^gP < 0.05, ^gggP < 0.001.