N-n-Butyl Haloperidol Iodide Ameliorates Cardiomyocytes Hypoxia/Reoxygenation Injury by Extracellular Calcium-Dependent and -Independent Mechanisms

Figure 2

Effects of F₂, Verapamil, and ERK1/2 inhibitors and activator on p-ERK1/2, total ERK1/2, and Egr-1 expression in extracellular-calcium-containing myocardial H/R by western-blot assay. (a) p-ERK1/2 and total ERK1/2; (b) Egr-1 protein. Quantitative densitometric data were expressed as percentages of the level observed in the CaCon group. All values are expressed as mean ± SEM of at least six individual experiments. ^∗𝑃<0.05 versus CaCon group; ^#𝑃<0.05 versus CaH/R group; ^†𝑃<0.05 versus CaH/R+F₂ group.

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(b)