Review Article

Phosphorylation of Tau Protein as the Link between Oxidative Stress, Mitochondrial Dysfunction, and Connectivity Failure: Implications for Alzheimer’s Disease

Figure 1

Neurofibrillary tangles are the classical hallmark of AD. Immunohistochemistry technique that evidences the most typical NFT that appears around affected areas (a, b). Here phosphorylated tau protein is the main element in the NFT aggregate scale bars 100 and 20 μm, respectively.
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(a)
940603.fig.001b
(b)