Oxidative Medicine and Cellular Longevity / 2013 / Article / Tab 2

Research Article

Cerebroprotective Effect of Moringa oleifera against Focal Ischemic Stroke Induced by Middle Cerebral Artery Occlusion

Table 2

Effect of Moringa oleifera leaves extract on foot withdrawal time in animal model of focal ischemic stroke ( ).

TreatmentFoot withdrawal time (seconds)
Days after MCAO
7 days14 days21 days

Vehicle + Sham operation1.84 ± 0.171.70 ± 0.151.88 ± 0.16
Vehicle + MCAO4.30 ± 0.63aaa3.79 ± 0.55aaa3.76 ± 0.20aaa
Piracetam + MCAO3.42 ± 0.353.12 ± 0.302.73 ± 0.07***
Vitamin C + MCAO2.48 ± 0.29**2.98 ± 0.272.71 ± 0.08***
M. oleifera 100 mg/kg + MCAO3.40 ± 0.272.60 ± 0.49*3.08 ± 0.20**
M. oleifera 200 mg/kg + MCAO3.17 ± 0.24*2.12 ± 0.33**2.27 ± 0.11***
M. oleifera 400 mg/kg + MCAO3.43 ± 0.382.42 ± 0.28**2.72 ± 0.24***

Data were expressed as mean ± SEM. P value < .001, compared to vehicle plus sham operation. P value < .05, .01, and .001, respectively, compared to vehicle plus MCAO.

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