Effects of Heat Acclimation on Changes in Oxidative Stress and Inflammation Caused by Endurance Capacity Test in the Heat

Table 1

The values of inflammation parameters before and after the endurance capacity test in the heat measured before and after heat acclimation program (𝑥  ± SD).

Parameters of inflammation	Non-heat-acclimated status		Heat-acclimated status		Main effect (𝐹)	𝑃 value
	Before EC test	After EC test	Before EC test	After EC test
hsCRP; mg/L	0.63±0.52	1.04±0.89^∗	1.17±2.59	3.53±4.64^∗	5.97	0.010
loghsCRP; mg/L	−0.32±0.32	−0.12±0.34^∗	−0.31±0.47	0.28±0.46^∗∗∗	14.76	0.000
sICAM-1; ng/mL	163.62±29.62	169.20±30.79	164.48±28.17	169.22±27.31	0.95	0.402
WBC; ×10^9/L	5.33±1.13	5.68±1.42	5.30±1.08	5.72±1.22	1.72	0.173
EGF; pg/mL	2.81±1.99	3.19±2.26	3.31±2.33	2.46±1.77	2.16	0.124
VEGF; pg/mL	53.14±45.04	54.99±36.04	54.87±35.89	45.87±29.38	1.16	0.325
MCP-1; protein-1 pg/mL	157.52±76.74	148.64±60.20	187.79±76.37	138.36±58.05^∗∗∗	6.10	0.001
IL-6; pg/mL	0.78±0.67	0.92±0.67	1.11±1.51	0.90±0.93	0.93	0.433
IL-8; pg/mL	8.55±12.25	9.93±17.48	9.92±13.05	8.30±12.63	2.11	0.152
𝛽2M; 𝜇g/L	1478.29±217.79	1465.42±204.64	1453.24±213.02	1528.18±280.28	1.73	0.538

Note: EC: endurance capacity; hsCRP: high-sensitive C-reactive protein; sICAM-1: soluble intercellular adhesion molecule-1; WBC: white blood cells; EGF: epidermal growth factor; VEGF: vascular endothelial growth factor; MCP-1: monocyte chemoattractant protein-1; IL-6: interleukin-6; IL-8: interleukin-8; 𝛽2M: 𝛽₂-microglobulin;  ^∗𝑃<0.05; ^∗∗∗𝑃<0.001 as compared to value measured before EC test.