Cardioprotection against Ischemia/Reperfusion by Licochalcone B in Isolated Rat Hearts

Table 2

Effect of licochalcone B on levels of CK and LDH in coronary flow of I/R injury (values are means with their standard deviation, ).

Physical index	Before ischemia	Reperfusion
	20 min	20 min	45 min
LDH (U/L)
Control	18.3 ± 4.67	17.1 ± 3.84	16.70 ± 7.17
I/R	17.6 ± 6.37	64.0 ± 4.67^##	58.5 ± 8.43^##
0.5 g/mL licochalcone B	17.79 ± 5.14	37.53 ± 6.61**	29.17 ± 5.61**
1 g/mL licochalcone B	17.6 ± 5.64	22.5 ± 6.49**	27.5 ± 7.26**
3 g/mL licochalcone B	17.60 ± 7.70	55.38 ± 2.75*	50.99 ± 3.42*
5 g/mL licochalcone B	19.35 ± 7.91	60.51 ± 8.54	53.34 ± 5.50
CK (U/L)
Control	28.19 ± 9.07	25.22 ± 5.89	26.02 ± 9.01
I/R	23.36 ± 7.55	366.98 ± 15.24^##	126.36 ± 14.13^##
0.5 g/mL licochalcone B	23.91 ± 3.95	276.47 ± 14.09**	93.54 ± 17.35**
1 g/mL licochalcone B	19.03 ± 11.12	243.63 ± 16.35**	72.00 ± 17.24**
3 g/mL licochalcone B	25.77 ± 9.73	310.97 ± 18.10	98.97 ± 14.89**
5 g/mL licochalcone B	27.49 ± 5.88	325.17 ± 18.33	106.27 ± 18.77

compared with the control group; and compared with I/R group.