Deletion of Metallothionein Exacerbates Intermittent Hypoxia-Induced Oxidative and Inflammatory Injury in Aorta
Figure 2
MT-KO mice exhibited earlier and more severe IH-induced aortic fibrosis. Aortic fibrosis was examined by immunohistochemical staining and qRT-PCR for the expression of CTGF (a) and immunohistochemical staining for TGF-β1 (b), followed by semiquantitative analysis. Data were presented as means ± SDs (); versus WT/C; # versus WT/IH. Bar = 50 μM.
