Table of Contents Author Guidelines Submit a Manuscript
Oxidative Medicine and Cellular Longevity
Volume 2014 (2014), Article ID 154295, 7 pages
http://dx.doi.org/10.1155/2014/154295
Research Article

Effect of Centella asiatica on Oxidative Stress and Lipid Metabolism in Hyperlipidemic Animal Models

1Medical College, Xiamen University, Xiang’an District, Xiamen 361000, China
2Xiamen Key Laboratory of Chiral Drugs, Xiamen 361000, China
3College of Pharmacy, Hubei University of Science and Technology, Xianning 437000, China

Received 14 February 2014; Revised 29 March 2014; Accepted 1 April 2014; Published 16 April 2014

Academic Editor: Si Jin

Copyright © 2014 Yun Zhao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. H. H. Chan, M.-H. Tai, C.-Y. Li, and J. Y. H. Chan, “Reduction in molecular synthesis or enzyme activity of superoxide dismutases and catalase contributes to oxidative stress and neurogenic hypertension in spontaneously hypertensive rats,” Free Radical Biology and Medicine, vol. 40, no. 11, pp. 2028–2039, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. W. P. Castelli, R. J. Garrison, P. W. F. Wilson, R. D. Abbott, S. Kalousdian, and W. B. Kannel, “Incidence of coronary heart disease and lipoprotein cholesterol levels. The Framingham study,” The Journal of the American Medical Association, vol. 256, no. 20, pp. 2835–2838, 1986. View at Google Scholar · View at Scopus
  3. D. Kuo, C. Yeh, P. Shieh, K. Cheng, F. Chen, and J. Cheng, “Effect of ShanZha, a Chinese herbal product, on obesity and dyslipidemia in hamsters receiving high-fat diet,” Journal of Ethnopharmacology, vol. 124, no. 3, pp. 544–550, 2009. View at Publisher · View at Google Scholar · View at Scopus
  4. Y. Hou, W. Shao, R. Xiao et al., “Pu-erh tea aqueous extracts lower atherosclerotic risk factors in a rat hyperlipidemia model,” Experimental Gerontology, vol. 44, no. 6-7, pp. 434–439, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. M. A. F. Jahromi, A. B. Ray, and J. P. N. Chansouria, “Antihyperlipidemic effect of flavonoids from Pterocarpus marsupium,” Journal of Natural Products, vol. 56, no. 7, pp. 989–994, 1993. View at Google Scholar · View at Scopus
  6. S. H. Thilakarathna and H. P. V. Rupasinghe, “Anti-atherosclerotic effects of fruit bioactive compounds: a review of current scientific evidence,” Canadian Journal of Plant Science, vol. 92, no. 3, pp. 407–419, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. B. Singh and R. P. Rastogi, “A reinvestigation of the triterpenes of Centella asiatica,” Phytochemistry, vol. 8, no. 5, pp. 917–921, 1969. View at Google Scholar · View at Scopus
  8. J. S. Guo, C. L. Cheng, and M. W. Koo, “Inhibitory effects of Centella asiatica water extract and asiaticoside on inducible nitric oxide synthase during gastric ulcer healing in rats,” Planta Medica, vol. 70, no. 12, pp. 1150–1154, 2004. View at Publisher · View at Google Scholar · View at Scopus
  9. M. H. V. Kumar and Y. K. Gupta, “Effect of different extracts of Centella asiatica on cognition and markers of oxidative stress in rats,” Journal of Ethnopharmacology, vol. 79, no. 2, pp. 253–260, 2002. View at Publisher · View at Google Scholar · View at Scopus
  10. T. D. Babu, G. Kuttan, and J. Padikkala, “Cytotoxic and anti-tumour properties of certain taxa of Umbelliferae with special reference to Centella asiatica (L.) urban,” Journal of Ethnopharmacology, vol. 48, no. 1, pp. 53–57, 1995. View at Publisher · View at Google Scholar · View at Scopus
  11. L. Lin, L. Liu, L. Chiang, and C. Lin, “In vitro anti-hepatoma activity of fifteen natural medicines from Canada,” Phytotherapy Research, vol. 16, no. 5, pp. 440–444, 2002. View at Publisher · View at Google Scholar · View at Scopus
  12. R. Gupta and S. J. S. Flora, “Effect of Centella asiatica on arsenic induced oxidative stress and metal distribution in rats,” Journal of Applied Toxicology, vol. 26, no. 3, pp. 213–222, 2006. View at Publisher · View at Google Scholar · View at Scopus
  13. Y. H. Siddique, G. Ara, T. Beg, M. Faisal, M. Ahmad, and M. Afzal, “Protective role of Centella asiatica L. extract against methyl methanesulphonate and cyclophosphamide induced genotoxic damage in cultured human lymphocytes,” Recent Progress in Medicinal Plants, vol. 19, no. 1, pp. 369–381, 2007. View at Publisher · View at Google Scholar
  14. P. Pakdeechote, S. Bunbupha, U. Kukongviriyapan, P. Prachaney, W. Khrisanapant, and V. Kukongviriyapan, “Asiatic acid alleviates hemodynamic and metabolic alterations via restoring eNOS/iNOS expression, oxidative stress, and inflammation in diet-induced metabolic syndrome rats,” Nutrients, vol. 6, no. 1, pp. 355–370, 2014. View at Publisher · View at Google Scholar
  15. K. H. Lin, Y. Y. Yang, C. M. Yang et al., “Antioxidant activity of herbaceous plant extracts protect against hydrogen peroxide-induced DNA damage in human lymphocytes,” BMC Research Notes, vol. 6, article 490, 2013. View at Publisher · View at Google Scholar
  16. Q. Liu, S. Liu, L. Li et al., “A dyslipidemia animal model induced by poloxamer 407 in golden hamsters and pilot study on the mechanism,” Acta Pharmaceutica Sinica, vol. 46, no. 4, pp. 406–411, 2011. View at Google Scholar · View at Scopus
  17. D. Yang, Y. Chang, C. Hsu, C. Liu, Y. Wang, and Y. Chen, “Protective effect of a litchi (Litchi chinensis Sonn.)-flower-water-extract on cardiovascular health in a high-fat/cholesterol-dietary hamsters,” Food Chemistry, vol. 119, no. 4, pp. 1457–1464, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. Q. L. Huang, Y. Jin, L. N. Zhang, P. C. K. Cheung, and J. F. Kennedy, “Structure, molecular size and antitumor activities of polysaccharides from Poria cocos mycelia produced in fermenter,” Carbohydrate Polymers, vol. 70, no. 3, pp. 324–333, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. W. Ibrahim, U.-S. Lee, C.-C. Yeh, J. Szabo, G. Bruckner, and C. K. Chow, “Oxidative stress and antioxidant status in mouse liver: effects of dietary lipid, vitamin E and iron,” Journal of Nutrition, vol. 127, no. 7, pp. 1401–1406, 1997. View at Google Scholar · View at Scopus
  20. S. Goldfarb, “Rapid increase in hepatic HMG CoA reductase activity and in vivo cholesterol synthesis after Triton WR-1339 injection,” Journal of Lipid Research, vol. 19, no. 4, pp. 489–494, 1978. View at Google Scholar · View at Scopus
  21. A. K. Khanna, F. Rizvi, and R. Chander, “Lipid lowering activity of Phyllanthus niruri in hyperlipemic rats,” Journal of Ethnopharmacology, vol. 82, no. 1, pp. 19–22, 2002. View at Publisher · View at Google Scholar · View at Scopus
  22. H. Harnafi, N. E. H. Bouanani, M. Aziz, H. S. Caid, N. Ghalim, and S. Amrani, “The hypolipidaemic activity of aqueous Erica multiflora flowers extract in Triton WR-1339 induced hyperlipidaemic rats: a comparison with fenofibrate,” Journal of Ethnopharmacology, vol. 109, no. 1, pp. 156–160, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. D. K. Spady, E. F. Stange, L. E. Bilhartz, and J. M. Dietschy, “Bile acids regulate hepatic low density lipoprotein receptor activity in the hamster by altering cholesterol flux across the liver,” Proceedings of the National Academy of Sciences of the United States of America, vol. 83, no. 6, pp. 1916–1920, 1986. View at Google Scholar · View at Scopus
  24. J. Y. Cherng and M. F. Shih, “Preventing dyslipidemia by Chlorella pyrenoidosa in rats and hamsters after chronic high fat diet treatment,” Life Sciences, vol. 76, no. 26, pp. 3001–3013, 2005. View at Publisher · View at Google Scholar · View at Scopus
  25. L. Calabresi, S. Simonelli, M. Gomaraschi, and G. Franceschini, “Genetic lecithin:cholesterol acyltransferase deficiency and cardiovascular disease,” Atherosclerosis, vol. 222, no. 2, pp. 299–306, 2012. View at Publisher · View at Google Scholar · View at Scopus
  26. D. J. Rader, E. T. Alexander, G. L. Weibel, J. Billheimer, and G. H. Rothblat, “The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis,” Journal of Lipid Research, vol. 50, supplement, pp. S189–S194, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. M. Nakhjavani, A. Morteza, R. Karimi, Z. Banihashmi, and A. Esteghamati, “Diabetes induces gender gap on LCAT levels and activity,” Life Sciences, vol. 92, no. 1, pp. 51–54, 2013. View at Publisher · View at Google Scholar
  28. K. F. Kozarsky, M. H. Donahee, A. Rigotti, S. N. Iqbal, E. R. Edelman, and M. Krieger, “Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels,” Nature, vol. 387, no. 6631, pp. 414–417, 1997. View at Publisher · View at Google Scholar · View at Scopus
  29. Y. Zhang, J. R. da Silva, M. Reiliy, J. T. Billheimer, G. H. Rothblat, and D. J. Rader, “Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo,” Journal of Clinical Investigation, vol. 115, no. 10, pp. 2870–2874, 2005. View at Publisher · View at Google Scholar · View at Scopus
  30. M. Ming, L. Guanhua, Y. Zhanhai, C. Guang, and Z. Xuan, “Effect of the Lycium barbarum polysaccharides administration on blood lipid metabolism and oxidative stress of mice fed high-fat diet in vivo,” Food Chemistry, vol. 113, no. 4, pp. 872–877, 2009. View at Publisher · View at Google Scholar · View at Scopus
  31. D. Bian, M. Liu, Y. Li, Y. Xia, Z. Gong, and Y. Dai, “Madecassoside, a triterpenoid saponin isolated from Centella asiatica herbs, protects endothelial cells against oxidative stress,” Journal of Biochemical and Molecular Toxicology, vol. 26, no. 10, pp. 399–406, 2012. View at Publisher · View at Google Scholar