Effect of Centella asiatica on Oxidative Stress and Lipid Metabolism in Hyperlipidemic Animal Models

Table 1

Effect of CA extracts on serum TC and TG levels in mice.

Groups	Dose (mg/kg d^−1)	TC (mmol/L)	TG (mmol/L)
NCG	—	2.39±0.09	0.26±0.03
HCG	—	6.61±0.62^##	14.00±1.67^###
HCG + Fen	100	4.07±0.70^∗	2.84±0.68^∗∗∗
HCG + CAE	1500	2.55±0.27^∗∗	4.69±2.11^∗∗∗
HCG + CAF1	1000	4.95±1.23	4.18±1.56^∗∗∗
HCG + CAF2	1000	6.83±1.13	6.99±0.90^∗∗∗
HCG + CAF3	1000	1.39±0.03^∗∗∗	0.65±0.18^∗∗∗

Values are expressed as means ± SEM (standard error of mean) from eight animals in each group; NCG: normal control group; HCG: hyperlipidemia control groups; HCG + Fen: hyperlipidemic + fenofibrate group; HCG + CAE: crude extract group; HCG + CAF1–HCG + CAF3: hyperlipidemic + fractions group.
^##𝑃<0.01, ^###𝑃<0.001 compared to NCG.
^∗𝑃<0.05, ^∗∗𝑃<0.01, ^∗∗∗𝑃<0.001 compared to HCG.