Effect of Centella asiatica on Oxidative Stress and Lipid Metabolism in Hyperlipidemic Animal Models

Table 3

Effect of CAF3 on serum lipid profile in hyperlipidemic golden hamsters.

Groups	Dose (mg/kg d^−1)	TC (mmol/L)	TG (mmol/L)	HDL-C (mmol/L)	LDL-C (mmol/L)	TC/HDL-C
NCD	—	1.75±0.15	0.54±0.10	1.16±0.19	2.55±0.25	1.71±0.26
HFD	—	7.13±1.15^###	1.52±0.16^###	3.22±0.28^###	9.68±1.33^###	2.46±0.22^#
HFD + XZK	250	4.10±0.32^∗∗∗	1.04±0.07^∗	2.70±0.17	5.32±0.26^∗∗∗	1.66±0.19^∗
HFD + C100	100	3.44±0.16^∗∗∗	0.81±0.08^∗∗∗	2.75±0.28	5.96±0.51^∗∗∗	1.40±0.20^∗∗
HFD + C250	250	2.76±0.18^∗∗∗	0.64±0.05^∗∗∗	2.93±0.15	3.68±0.33^∗∗∗	0.91±0.08^∗∗∗
HFD + C500	500	3.69±0.61^∗∗∗	1.17±0.21^∗	2.60±0.13	3.04±0.12^∗∗∗	1.35±0.21^∗∗

Values are expressed as means ± SEM from 8 animals each group; NCD: normal chow diet group; HFD: high-fat diet group; HFD + XZK: high-Fat diet + Xuezhikang group; HFD + C100, HFD + C250, HFD + C500: high-fat diet + CAF3 (100, 250, 500 mg/kg) group, respectively.
^#𝑃<0.05, ^###𝑃<0.001 compared to NCD.
^∗𝑃<0.05, ^∗∗𝑃<0.01, ^∗∗∗𝑃<0.001 compared to HFD.