Oxidative Medicine and Cellular Longevity / 2014 / Article / Fig 6

Research Article

Decitabine and SAHA-Induced Apoptosis Is Accompanied by Survivin Downregulation and Potentiated by ATRA in p53-Deficient Cells

Figure 6

(a) Viability, subG1 cell fraction, and ROS production in control cells and after 48 h ATRA, DAC + SAHA or DAC + SAHA + ATRA treatment of CML-T1 leukemic cell line. Error bars represent ±SEM of at least three measurements. (b) Fragmentation of PARP, expression of tumor suppressor p53, and proteins related to apoptosis monitored in CML-T1 cells by immunoblotting. Images are representatives of three experiments with similar results.

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.