Serum Oxidative Stress Markers and Lipidomic Profile to Detect NASH Patients Responsive to an Antioxidant Treatment: A Pilot Study

Table 4

Assignments of the m/z ratios detected in the positive ion MALDI-TOF mass spectra of the organic extracts of serum patient NASH before (T0) and after 12 months of chronic administration of RA (T12).

m/z (MH^+)	Identity	CTR	Group 1		Group 2
			T0	T12	T0	T12
496,36	lyso PC 16:0	100	100	100	100	100
369,37	CL (−H2O) (H^+)	68±5	35±3	16±1	15±7	41±5
520,4	lyso PC 18:2	37±3	12±2	2±1	11±3	9±4
522,41	lyso PC 18:1	30±3	18±5	17±5	17±4	15±6
524,37	lyso PC 18:0	31±4	32±5	30±3	30±4	59±6
703,5	SM 16:0	20±5	5±6	1±1	8±5	18±2
758,65	PC 16:0/18:2	104±4	21±5	8±2	19±4	64±10
760,51	PC 16:0/18:1 (H^+)	42±5	24±4	13±5	8±2	27±4
784,66	PC 18:1/18:2	43±5	13±3	5±2	9±4	34±4
786,53^#	PC 18:0/18:2 (H^+)/ PC 18:1/18:1 (H^+)	40±6	9±1	4±1.5	6±2	18±3
804,52	PC 18:2/18:2 (Na^+)	9±1	2±0.5	1±0.75	2±1	10±0.5
808,55^#	PC 18:0/18:2 (Na^+)/PC 18:1/20:4 (H^+)	19±2	3±0.5	9±1	5±1	19±2
810,55	PC 18:0/20:4	25±3	5±1	3±1	5±2	18±3
812,62	PC 18:0/20:3	12±1	5±0.5	22±5	3±1	16±4

Quantitative determination in % made ​​only on the basis of the value of H⁺ or Na⁺.
^#Identification is not unique (there are two possible identities).
CL = free cholesterol; lyso-PC = lysophosphatidylcholine; PC = phosphatidylcholine; SM = sphingomyelin.