Leptin Level and Oxidative Stress Contribute to Obesity-Induced Low Testosterone in Murine Testicular Tissue

Table 2

The retroperitoneal, epididymal fat weight and reproductive organs weight in 8 weeks and 19 weeks (𝑥  ± SD).

Group

𝑛

Ret. fat (g)

Relative Ret. fat (g/100 g)

Epi. fat (g)

Relative Epi. fat (g/100 g)

Tes. weight (g)

Relative Tes. weight (g/100 g)

Epididymis weight (g)

Relative epididymis weight (g/100 g)

Sem. weight (g)

Relative Sem. weight (g/100 g)

8 weeks

DIO

12

0.09 ± 0.03**

0.34 ± 0.13**

0.32 ± 0.09**

1.23 ± 0.29**

0.19 ± 0.02

0.77 ± 0.06^*#

0.07 ± 0.01

0.29 ± 0.06

0.22 ± 0.02*

0.87 ± 0.11^##

DIO-R

12

0.08 ± 0.03**

0.37 ± 0.13**

0.32 ± 0.07**

1.49 ± 0.25**

0.18 ± 0.01

0.86 ± 00.07

0.07 ± 0.01

0.31 ± 0.02

0.24 ± 0.03**

1.12 ± 0.15

Control

12

0.03 ± 0.01

0.12 ± 0.04

0.19 ± 0.04

0.91 ± 0.18

0.18 ± 0.03

0.85 ± 0.10

0.06 ± 0.01

0.31 ± 0.05

0.19 ± 0.03

0.91 ± 0.16^##

19 weeks

DIO

12

0.49 ± 0.19**

1.49 ± 0.55**

1.15 ± 0.34**

3.52 ± 0.99**

0.20 ± 0.02

0.62 ± 0.08^**##

0.08 ± 0.01

0.25 ± 0.05**

0.31 ± 0.07

0.96 ± 0.21

DIO-R

12

0.20 ± 0.06**

0.73 ± 0.22**

0.62 ± 0.19**

2.27 ± 0.67**

0.20 ± 0.01

0.72 ± 0.05

0.07 ± 0.01

0.27 ± 0.05

0.28 ± 0.060

1.02 ± 0.23

Control

12

0.077 ± 0.037

0.28 ± 0.12

0.33 ± 0.06

1.19 ± 0.19

0.20 ± 0.02

0.75 ± 0.07

0.08 ± 0.01

0.30 ± 0.02

0.27 ± 0.06

1.01 ± 0.21

Note. Data are mean ± SD; ^∗𝑃<0.05 and ^∗∗𝑃<0.01 denote statistical significance compared with control group; ^#𝑃<0.05 and ^##𝑃<0.01 denote statistical significance compared with DIO-R group. Ret: retroperitoneal; Epi: epididymal; Tes: testis; Sem: seminal vesicles.
Relative ret. weight = retroperitoneal fat weight/body weight × 100. Relative Epi. fat weight = epididymal fat weight/body weight × 100. Relative Tes. weight = testis weight/body weight × 100. Relative epididymis weight = epididymis weight/body weight × 100. Relative Sem. weight = seminal vesicles weight/body weight × 100.