Redox Imbalance and Morphological Changes in Skin Fibroblasts in Typical Rett Syndrome

<table>Increased levels of total (i.e., sum of free and esterified form) F<sub>2</sub>-IsoPs, total F<sub>4</sub>-NeuroPs, 4-HNE PAs, and NPBI in RTT skin fibroblast as compared to the control cells. <svg height="17.825001" id="M11" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 85.474998 17.825001" width="85.474998" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>. Data are expressed as means ± standard deviation. Legend: F<sub>2</sub>-IsoPs, F<sub>2</sub>-isoprostanes; F<sub>4</sub>-NeuroPs, F<sub>4</sub>-neuroprostanes; 4-HNE PAs, 4-hydroxy-2-nonenal protein adducts; NPBI, nonprotein bound iron.</table>

Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: Redox Imbalance and Morphological Changes in Skin Fibroblasts in Typical Rett Syndrome 