Magnolia Extract (BL153) Protection of Heart from Lipid Accumulation Caused Cardiac Oxidative Damage, Inflammation, and Cell Death in High-Fat Diet Fed Mice

Table 1

The effects of BL153 on cardiac function in HFD feeding mice.

	Control	HFD	HFD + 2.5 mg/kg	HFD + 5.0 mg/kg	HFD + 10 mg/kg
IVS; d (mm)	0.72±0.03	0.71±0.03	0.69±0.02	0.70±0.03	0.70±0.0232
LVID; d (mm)	3.26±0.18	3.61±0.25	3.61±0.17	3.68±0.21	3.72±0.23
LVPW; d (mm)	0.80±0.10	0.85±0.08	0.99±0.08	0.89±0.18	0.96±0.10
IVS; s (mm)	1.10±0.02	1.16±0.15	1.03±0.12	1.13±0.17	1.19±0.10
LVID; s (mm)	1.37±0.23	1.72±0.36	1.77±0.35	1.82±0.25	1.60±0.19
LVPW; s (mm)	0.50±0.24	1.48±0.34	1.74±0.25	1.55±0.26	1.79±0.20
LV vol; d (𝜇L)	43.16±5.55	55.49±9.08	55.05±5.90	57.83±8.07	59.40±8.56
LV vol; s (𝜇L)	4.98±2.04	9.40±4.69	10.06±4.73	10.54±4.03	7.60±2.29
%EF	88.76±3.29	82.59±10.14	81.71±8.58	82.18±4.45	87.44±3.15
%FS	58.24±4.59	52.25±11.21	50.99±10.22	50.80±4.69	57.13±4.15
LV mass (mg)	79.02±3.31	97.10±15.86	106.85±13.03	101.68±18.27	110.94±18.34
HR (beats/min)	697.93±53.40	677.98±50.60	689.18±34.90	675.86±36.11	667.95±27.90
Systolic BP (mmHg)	110.92±5.13	113.09±3.71	97.90±11.34	98.79±10.41	109.39±5.48
Diastolic BP (mmHg)	79.69±6.99	77.30±5.65	69.75±10.10	70.68±10.27	79.34±4.75
Mean BP (mmHg)	89.76±6.35	88.92±3.82	78.79±10.46	79.73±10.30	89.03±4.84

Notes. IVS: interventricular septum; LVID; d: left ventricular end diastolic diameter; LVID; s: left ventricular end systolic diameter; LVPW: left ventricular posterior wall; EF: ejection fraction; FS: fractional shortening; LV vol; s: left ventricular end systolic volume; LV vol; d: left ventricular end diastolic volume; LV mass: left ventricular mass. HR: heart rate; BP: blood pressure. Data were presented as means ± SEM (𝑛=5).