Effects of Paracetamol on NOS, COX, and CYP Activity and on Oxidative Stress in Healthy Male Subjects, Rat Hepatocytes, and Recombinant NOS
Figure 6
Effect of paracetamol (APAP) at 100 μM (15 mg/L) on the formation of [15N]nitrite and [15N]nitrate in an incubation mixture of recombinant heNOS upon incubation time (a) and linear regression analysis between [15N]nitrite and [15N]nitrate concentrations measured in the presence and absence of paracetamol (b). Data in (a) are shown as mean ± SD from two independent experiments; no statistical analysis was performed.
