The Protective Effects of Shen-Fu Injection on Experimental Acute Pancreatitis in a Rat Model

Figure 5

Histological evaluation. (a) Light microscope observations of H&E stained sections (×200). (A) Control group: normal pancreatic structure was observed. (B) Caerulein group: severe edema, inflammation cell infiltration, and acinar necrosis were noted. (C), (D), and (E) SFI subgroup 1–3, respectively: SFI treatments reduced pancreatic edema, inflammation and acinar necrosis. (b) Histological scores. Morphological injuries to pancreas were evaluated through five main aspects: edema, acinar necrosis, inflammatory cell infiltration, hemorrhage, fat necrosis, and perivascular inflammation. SFI treated groups showed significantly lower scores of those parameters except the fat necrosis. Compared with caerulein group, ^∗𝑃<0.05, ^∗∗𝑃<0.01; compared with control group, ^#𝑃<0.05, ^##𝑃<0.01.

(a)

(b)