Oxidative Damage to Nucleic Acids and Benzo(a)pyrene-7,8-diol-9,10-epoxide-DNA Adducts and Chromosomal Aberration in Children with Psoriasis Repeatedly Exposed to Crude Coal Tar Ointment and UV Radiation

Table 4

The associations between monitored biomarkers (levels after GT) and important characteristics of exposure (Spearman Rank Order Correlations).

	Total duration; of GT; (days)	Time of UVR exposure; (days)	Daily topical application of CCT ointment (% of body surface)
Oxidative damage of DNA and RNA^a	NS	NS	NS
BPDE-DNA adducts^b	NS	NS
Total number of aberrated cells^c	NS		NS
PASI score^d	NS	NS

^aUnit: pg of the sum of three oxidized guanine species per ml of serum.
^bUnit: ng of BPDE-DNA adducts per g of DNA.
^cUnit: percentage of total number of aberrated cells (ABC).
^dDimensionless.