Saponins from <i>Aralia taibaiensis</i> Attenuate D-Galactose-Induced Aging in Rats by Activating FOXO3a and Nrf2 Pathways

<table>Saponins supplementation activated Nrf2 pathway in liver of D-galactose-induced aging rats. The protein levels of p-Nrf2 and Nrf2 (a), as well as its targeted genes HO-1, GCLC, and GCLM (b), were determined by Western blot. The band intensities were quantified by Quantity One Software version 4.6.3. Protein levels were normalized to <i>β</i>-actin or Lamin B as compared with the untreated Control (set to 1). Data are expressed as mean ± SD; <svg height="11.6" id="M19" style="vertical-align:-0.546pt" version="1.1" viewbox="0 0 36.237499 11.6" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>. Intergroup comparisons were performed by ANOVA. <svg height="13.95" id="M20" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 66.324997 13.95" width="66.324997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> versus D-gal.</table>

Oxidative Medicine and Cellular Longevity

fig6

Figure 6

Figure 6: Saponins from <i>Aralia taibaiensis</i> Attenuate D-Galactose-Induced Aging in Rats by Activating FOXO3a and Nrf2 Pathways 

Oxidative Medicine and Cellular Longevity

Saponins from Aralia taibaiensis Attenuate D-Galactose-Induced Aging in Rats by Activating FOXO3a and Nrf2 Pathways

Figure 6