Research Article

Anticonvulsant and Antioxidant Effects of Tilia americana var. mexicana and Flavonoids Constituents in the Pentylenetetrazole-Induced Seizures

Table 3

Scavenging capacity of the hexane, methanol, and aqueous extracts from Tilia inflorescences and references compounds.

SpeciesHexaneMethanolAqueousReference compound

IC50 (g/mL)IC50 (g/mL)IC50 (g/mL)IC50 (g/mL)
70.21 ± 1.21*51.11 ± 1.82*421.82 ± 7.85*NDGA1.027 ± 0.165
HOCl92.97 ± 3.43*173.46 ± 2.59*5764.83 ± 1341.1*Ascorbic acid0.50 ±0.005
H2O234.48 ± 1.60*59.41 ± 2.57*1926.8 ± 1284.77*Pyruvate0.120 ± 0.094
1O23.75 ± 1.10*7.46 ± 1.28*10897.1 ± 1171.21*GSH7.58 ± 0.25
HO>146.845.13 ± 1.94*>10130DMTU1.22 ± 0.01

Data are represented as the mean ± SE of three independent assays. ANOVA followed by Dunnett’s test. * versus reference compounds.