Research Article

Anticonvulsant and Antioxidant Effects of Tilia americana var. mexicana and Flavonoids Constituents in the Pentylenetetrazole-Induced Seizures

Table 4

Scavenging capacity of the hexane and methanol extracts of Tilia leaves and reference compounds.

SpeciesHexaneMethanolReference compound

IC50 (g/mL)IC50 (g/mL)IC50 (g/mL)
57.32 ± 0.58*27.64 ± 1.61*NDGA1.027 ± 0.165
HOCl16.67 ± 1.89*225.26 ± 5.30*Ascorbic acid0.50 ± 0.005
H2O297.96 ± 4.10*73.25 ± 3.02*Pyruvate0.120 ± 0.094
1O223.28 ± 1.15*0.80 ± 0.001*GSH7.58 ± 0.25
H172.4 ± 2.05+60.12 ± 1.98*DMTU1.22 ± 0.01

Data are represented as the mean ± SE of three independent assays. ANOVA followed by Dunnett’s test. * versus reference compounds.