A Novel Contrast-Induced Acute Kidney Injury Model Based on the 5/6-Nephrectomy Rat and Nephrotoxicological Evaluation of Iohexol and Iodixanol In Vivo

Figure 5

Iohexol resulted in a more significant reduction of renal function compared with iodixanol in 5/6 NE rats. Changes in the levels of (a) BP, (b) Scr, (c) BUN, and (d) Ccr before and at 24 h, 48 h, and 72 h after an intravenous injection of saline, iohexol, or iodixanol. and versus the control group; .

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