Oxidative Medicine and Cellular Longevity / 2014 / Article / Tab 3

Research Article

Lack of Association between Nuclear Factor Erythroid-Derived 2-Like 2 Promoter Gene Polymorphisms and Oxidative Stress Biomarkers in Amyotrophic Lateral Sclerosis Patients

Table 3

Distributions of genotypes and allele frequencies in SNP −617 C/A in ALS patients and in controls.

sALS patients Controls test value

Genotypes −617 C/A : 145 : 168
 CC109 (75.2%)123 (73.2%)
 CA34 (23.4%)41 (24.4%)
 AA2 (1.4%)4 (2.4%)
 CA + AA36 (24.8%)45 (26.8%)0.090.7
 Allele A frequency 0.280.59
Males : 88 : 84
 CC62 (70.4%)59 (70.3%)
 CA24 (27.3%)21 (25%)
 AA2 (2.3%)4 (4.7%)
 CA + AA26 (29.6%)25 (29.7%)0.0010.98
 Allele A frequency 0.090.75
Females : 57 : 84
 CC47 (82.5%)64 (76.2%)
 CA10 (17.5%)20 (23.8%)
 AA00
 CA + AA10 (17.5%)20 (23.8%)0.50.47
 Allele A frequency 0.70.4

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