The Attenuation of Moutan Cortex on Oxidative Stress for Renal Injury in AGEs-Induced Mesangial Cell Dysfunction and Streptozotocin-Induced Diabetic Nephropathy Rats

Figure 6

Attenuation of MC on AGEs-induced ROS generation in HBZY-1 mesangial cell. (a) BSA (200 𝜇g mL⁻¹); (b) AGEs (200 𝜇g mL⁻¹); (c) AG (10 𝜇M) + AGEs (200 𝜇g mL⁻¹); (d) VE (10 𝜇M) + AGEs (200 𝜇g mL⁻¹); (e) MC (2×10⁻⁴ g mL⁻¹) + AGEs (200 𝜇g mL⁻¹); (f) MC (10⁻⁴ g mL⁻¹) + AGEs (200 𝜇g mL⁻¹); (g) MC (5×10⁻⁵ g mL⁻¹) + AGEs (200 𝜇g mL⁻¹); (h) MC (2.5×10⁻⁵ g mL⁻¹) + AGEs (200 𝜇g mL⁻¹); (i) MC (1.25×10⁻⁵ g mL⁻¹) + AGEs (200 𝜇g mL⁻¹); (j) negative.

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