The Attenuation of Moutan Cortex on Oxidative Stress for Renal Injury in AGEs-Induced Mesangial Cell Dysfunction and Streptozotocin-Induced Diabetic Nephropathy Rats

Figure 8

Effect of MC on AGEs-induced oxidant stress in HBZY-1 mesangial cell. (a) The effect of MC on AGEs-induced CAT activity; (b) the effect of MC on AGE-induced GSH-Px activity; (c) the effect of MC on AGEs-induced SOD activity; (d) the effect of MC on AGEs-induced MDA content. ^&&&𝑃<0.001, ^&&𝑃<0.01, and ^&𝑃<0.05, AGEs versus BSA; ^𝜑𝜑𝑃<0.01 and ^𝜑𝑃<0.05, AG versus AGEs; ^∗∗𝑃<0.01 and ^∗𝑃<0.05, VE versus AGEs; ^###𝑃<0.001, ^##𝑃<0.01, ^#𝑃<0.05, and 2×10⁻⁴ g mL⁻¹ versus model, 10⁻⁴ g mL⁻¹ versus model. 5×10⁻⁵ g mL⁻¹ versus model, 2.5×10⁻⁵ g mL⁻¹ versus model, and 1.25×10⁻⁵ g mL⁻¹ versus model. Data from individual experiments are presented as means ± SD (𝑛=3).

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