The Attenuation of Moutan Cortex on Oxidative Stress for Renal Injury in AGEs-Induced Mesangial Cell Dysfunction and Streptozotocin-Induced Diabetic Nephropathy Rats

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td align="left">No.</td><td align="center">Group</td><td align="center">kinds of rats</td><td align="center">Drugs </td><td align="center">Dose <br/>(g kg<sup>−1</sup>)</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td align="left">1</td><td align="center">Control</td><td align="center">Normal</td><td align="center">Normal saline</td><td align="center">0.1</td></tr><tr><td align="left">2</td><td align="center">Model</td><td align="center">DN</td><td align="center">Normal saline</td><td align="center">0.1</td></tr><tr><td align="left">3</td><td align="center">Positive control (<svg height="10.9125" id="M12" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 8.2875004 10.9125" width="8.2875004" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,10.862)"><path d="M384 0h-275v27q67 5 81.5 18.5t14.5 68.5v385q0 38 -7.5 47.5t-40.5 10.5l-48 2v24q85 15 178 52v-521q0 -55 14.5 -68.5t82.5 -18.5v-27z" id="x31"></path></g>
</svg>)</td><td align="center">DN</td><td align="center">AG</td><td align="center">0.1</td></tr><tr><td align="left">4</td><td align="center">Positive control (<svg height="10.9125" id="M13" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 8.2875004 10.9125" width="8.2875004" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,10.862)"><path d="M412 140l28 -9q0 -2 -35 -131h-373v23q112 112 161 170q59 70 92 127t33 115q0 63 -31 98t-86 35q-75 0 -137 -93l-22 20l57 81q55 59 135 59q69 0 118.5 -46.5t49.5 -122.5q0 -62 -29.5 -114t-102.5 -130l-141 -149h186q42 0 58.5 10.5t38.5 56.5z" id="x32"></path></g>
</svg>)</td><td align="center">DN</td><td align="center">VE</td><td align="center">0.1</td></tr><tr><td align="left">5</td><td align="center">High dose </td><td align="center">DN</td><td align="center">Moutan Cortex</td><td align="center">5</td></tr><tr><td align="left">6</td><td align="center">Medium dose</td><td align="center">DN</td><td align="center">Moutan Cortex</td><td align="center">2.5</td></tr><tr><td align="left">7</td><td align="center">Low dose </td><td align="center">DN </td><td align="center">Moutan Cortex</td><td align="center">1.25</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Definition of rats experimental groups (<svg height="11.225" id="M11" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 36.237499 11.225" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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q42 56 97 103.5t96 71.5q46 26 74 26q9 0 16 -2.5t14 -11.5t9.5 -24.5t-1 -44t-13.5 -68.5q-30 -117 -47 -200q-4 -19 -3.5 -25t6.5 -6q21 0 70 48z" id="x1D45B"></path></g><g transform="matrix(.017,-0,0,-.017,13.305,10.963)"><path d="M535 323h-483v50h483v-50zM535 138h-483v50h483v-50z" id="x3D"></path></g><g transform="matrix(.017,-0,0,-.017,28.008,10.963)"><path d="M137 343l67 33q37 17 63 17q79 0 129.5 -53t50.5 -131q0 -92 -58 -156.5t-147 -64.5t-147 68t-58 182q0 63 17 119t43 95.5t61.5 72t69 52t67.5 31.5q62 22 128 33l6 -32q-56 -11 -108 -35q-149 -71 -184 -231zM227 337q-47 0 -95 -27q-6 -23 -6 -70q0 -93 36 -155.5
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</svg>/group).

Oxidative Medicine and Cellular Longevity

tab1

Table 1

Table 1: The Attenuation of Moutan Cortex on Oxidative Stress for Renal Injury in AGEs-Induced Mesangial Cell Dysfunction and Streptozotocin-Induced Diabetic Nephropathy Rats 

Table 1 | The Attenuation of Moutan Cortex on Oxidative Stress for Renal Injury in AGEs-Induced Mesangial Cell Dysfunction and Streptozotocin-Induced Diabetic Nephropathy Rats 