Resveratrol Inhibits Phenotype Modulation by Platelet Derived Growth Factor-bb in Rat Aortic Smooth Muscle Cells
Figure 4
Morphology modulation by resveratrol in PDGF-bb-stimulated RAOSMCs. (a) The distribution of circularity ranged from 0 to 1, for linear to circular, respectively. (—in serum free, —•— in 10 ng/mL PDGF-bb, and ••••• in 10 ng/mL PDGF-bb with 20 μM resveratrol). (b) The average circularity SD was obtained from 100 single cells per each type. compared with nonstimulated control; compared with 10 ng/mL PDGF-bb-stimulated control. (c) The average area (μm2/cell) SD was obtained from 100 single cells of each type. compared with nonstimulated control; compared with 10 ng/mL PDGF-bb-stimulated control.