Isoprostanes and Neuroprostanes as Biomarkers of Oxidative Stress in Neurodegenerative Diseases

Table 1

Isoprostanes as markers of oxidative stress in neurodegenerative diseases.

Classes of isoprostanes	Material	Disease	Study	Versus control	Reference
F2-IsoPs	CSF*, post; mortem brain; tissue, plasma, urinary	Alzheimer disease	vivo	High	[10–13, 32]
		Creutzfeldt-Jakob	vivo/vitro	High	[17, 18, 53]
		Huntington disease	vivo	High	[54]
8-iso PGF 2alfa	Urine	SPMS**	vivo	6-fold	[55]
	CSF	RRMS***	vivo	Higher	[9, 53, 56, 57]
		ALS****	vivo	Higher	[5, 19, 58]

CSF*: cerebrospinal fluid; SPMS**: secondary-progressive type of multiple sclerosis; RRMS***: relapsing-remitting type of multiple sclerosis. ALS****: amyotrophic lateral sclerosis.