Table of Contents Author Guidelines Submit a Manuscript
Oxidative Medicine and Cellular Longevity
Volume 2014 (2014), Article ID 579305, 9 pages
http://dx.doi.org/10.1155/2014/579305
Research Article

Antiosteoporotic Effect of Combined Extract of Morus alba and Polygonum odoratum

1Department of Physiology and Graduate School (Neuroscience Program), Faculty of Medicine, Khon Kaen University, Khon Kaen 40000, Thailand
2Integrated Complementary Alternative Medicine Research and Development Center, Khon Kaen University, Khon Kaen 40000, Thailand
3Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40000, Thailand

Received 7 August 2014; Revised 11 October 2014; Accepted 15 October 2014; Published 12 November 2014

Academic Editor: Liang-Jun Yan

Copyright © 2014 Sudarat Sungkamanee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. C. Cooper, G. Campion, and L. J. Melton III, “Hip fractures in the elderly: a world-wide projection,” Osteoporosis International, vol. 2, no. 6, pp. 285–289, 1992. View at Google Scholar
  2. L. M. Chiechi and L. Micheli, “Utility of dietary phytoestrogens in preventing postmenopausal osteoporosis,” Current Topics in Nutraceutical Research, vol. 3, no. 1, pp. 15–28, 2005. View at Google Scholar · View at Scopus
  3. D. J. Becker, M. L. Kilgore, and M. A. Morrisey, “The societal burden of osteoporosis,” Current Rheumatology Reports, vol. 12, no. 3, pp. 186–191, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. A. F. Al-Anazi, V. F. Qureshi, K. Javaid, and S. Qureshi, “Preventive effects of phytoestrogens against postmenopausal osteoporosis as compared to the available therapeutic choices: an overview,” Journal of Natural Science, Biology and Medicine, vol. 2, no. 2, pp. 154–163, 2011. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Gambacciani and F. Vacca, “Postmenopausal osteoporosis and hormone replacement therapy,” Minerva Medica, vol. 95, no. 6, pp. 507–520, 2004. View at Google Scholar · View at Scopus
  6. G. Banfi, E. L. Iorio, and M. M. Corsi, “Oxidative stress, free radicals and bone remodeling,” Clinical Chemistry and Laboratory Medicine, vol. 46, no. 11, pp. 1550–1555, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. C. J. Jagger, J. M. Lean, J. T. Davies, and T. J. Chambers, “Tumor necrosis factor-α mediates osteopenia caused by depletion of antioxidants,” Endocrinology, vol. 146, no. 1, pp. 113–118, 2005. View at Publisher · View at Google Scholar · View at Scopus
  8. S. Ozgocmen, H. Kaya, E. Fadillioglu, R. Aydogan, and Z. Yilmaz, “Role of antioxidant systems, lipid peroxidation, and nitric oxide in postmenopausal osteoporosis,” Molecular and Cellular Biochemistry, vol. 295, no. 1-2, pp. 45–52, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. N. Mody, F. Parhami, T. A. Sarafian, and L. L. Demer, “Oxidative stress modulates osteoblastic differentiation of vascular and bone cells,” Free Radical Biology and Medicine, vol. 31, no. 4, pp. 509–519, 2001. View at Publisher · View at Google Scholar · View at Scopus
  10. K. Doi, T. Kojima, and Y. Fujimoto, “Mulberry leaf extract inhibits the oxidative modification of rabbit and human low density lipoprotein,” Biological and Pharmaceutical Bulletin, vol. 23, no. 9, pp. 1066–1071, 2000. View at Publisher · View at Google Scholar · View at Scopus
  11. H. B. Kim, C. K. Kang, G. B. Sung, S. W. Kang, and J. Lee, “Anti-oxidative capacity of mulberry leaf and its tea,” The Korean Journal of Sericultural Science, vol. 49, no. 1, pp. 18–23, 2007. View at Google Scholar
  12. B. Enkhmaa, K. Shiwaku, T. Katsube et al., “Mulberry (Morus alba L.) leaves and their major flavonol quercetin 3-(6-malonylglucoside) attenuate atherosclerotic lesion development in LDL receptor-deficient mice,” Journal of Nutrition, vol. 135, no. 4, pp. 729–734, 2005. View at Google Scholar · View at Scopus
  13. S. Nanasombat and N. Teckchuen, “Antimicrobial, antioxidant and anticancer activities of Thai local vegetables,” Journal of Medicinal Plants Research, vol. 3, no. 5, pp. 443–449, 2009. View at Google Scholar · View at Scopus
  14. A. A. Basma, Z. Zakaria, L. Y. Latha, and S. Sasidharan, “Antioxidant activity and phytochemical screening of the methanol extracts of Euphorbia hirta L,” Asian Pacific Journal of Tropical Medicine, vol. 4, no. 5, pp. 386–390, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. F. Pourmorad, S. J. Hosseinimehr, and N. Shahabimajd, “Antioxidant activity, phenol and flavonoid contents of some selected Iranian medicinal plants,” African Journal of Biotechnology, vol. 5, no. 11, pp. 1142–1145, 2006. View at Google Scholar · View at Scopus
  16. B. K. Potu, M. S. Rao, G. K. Nampurath, M. R. Chamallamudi, S. R. Nayak, and H. Thomas, “Anti-osteoporotic activity of the petroleum ether extract of Cissus quadrangularis Linn. in ovariectomized wistar rats,” Chang Gung Medical Journal, vol. 33, no. 3, pp. 252–257, 2010. View at Google Scholar · View at Scopus
  17. M. A. Abujazia, N. Muhammad, A. N. Shuid, and I. N. Soelaiman, “The effects of virgin coconut oil on bone oxidative status in ovariectomised rat,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, Article ID 525079, 6 pages, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. H. Ohkawa, N. Ohishi, and K. Yagi, “Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction,” Analytical Biochemistry, vol. 95, no. 2, pp. 351–358, 1979. View at Publisher · View at Google Scholar · View at Scopus
  19. J. M. McCord and I. Fridovich, “Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein),” The Journal of Biological Chemistry, vol. 244, no. 22, pp. 6049–6055, 1969. View at Google Scholar · View at Scopus
  20. K. Dundar, T. Topal, H. Ay, S. Oter, and A. Korkmaz, “Protective effects of exogenously administered or endogenously produced melatonin on hyperbaric oxygen-induced oxidative stress in the rat brain,” Clinical and Experimental Pharmacology and Physiology, vol. 32, no. 11, pp. 926–930, 2005. View at Publisher · View at Google Scholar · View at Scopus
  21. P. P. Lelovas, T. T. Xanthos, S. E. Thorma, G. P. Lyritis, and I. A. Dontas, “The laboratory rat as an animal model for osteoporosis research,” Comparative Medicine, vol. 58, no. 5, pp. 424–430, 2008. View at Google Scholar · View at Scopus
  22. N. Li, L. P. Qin, T. Han, Y. B. Wu, Q. Y. Zhang, and H. Zhang, “Inhibitory effects of Morinda officinalis extract on bone loss in ovariectomized rats,” Molecules, vol. 14, no. 6, pp. 2049–2061, 2009. View at Google Scholar
  23. H. W. McGowan, J. A. Schuijers, B. L. Grills, S. J. McDonald, and A. C. McDonald, “Galnon, a galanin receptor agonist, improves intrinsic cortical bone tissue properties but exacerbates bone loss in an ovariectomised rat model,” Journal of Musculoskeletal Neuronal Interactions, vol. 14, no. 2, pp. 162–172, 2014. View at Google Scholar · View at Scopus
  24. C. Ohlsson, C. Engdahl, F. Fak et al., “Probiotics protect mice from ovariectomy-induced cortical bone loss,” PLoS ONE, vol. 9, no. 3, Article ID e92368, 2014. View at Publisher · View at Google Scholar · View at Scopus
  25. D. J. Rickard, F.-L. Wang, A.-M. Rodriguez-Rojas et al., “Intermittent treatment with parathyroid hormone (PTH) as well as a non-peptide small molecule agonist of the PTH1 receptor inhibits adipocyte differentiation in human bone marrow stromal cells,” Bone, vol. 39, no. 6, pp. 1361–1372, 2006. View at Publisher · View at Google Scholar · View at Scopus
  26. C. J. Rosen, “What's new with PTH in osteoporosis: where are we and where are we headed?” Trends in Endocrinology & Metabolism, vol. 15, no. 5, pp. 229–233, 2004. View at Publisher · View at Google Scholar · View at Scopus
  27. E. J. Mackie, “Osteoblasts: novel roles in orchestration of skeletal architecture,” The International Journal of Biochemistry and Cell Biology, vol. 35, no. 9, pp. 1301–1305, 2003. View at Publisher · View at Google Scholar · View at Scopus
  28. C. M. Gundberg, J. B. Lian, and S. L. Booth, “Vitamin K-dependent carboxylation of osteocalcin: friend or foe?” Advances in Nutrition, vol. 3, no. 2, pp. 149–157, 2012. View at Publisher · View at Google Scholar · View at Scopus
  29. S. Srivastava, R. Kapoor, A. Thathola, and R. P. Srivastava, “Nutritional quality of leaves of some genotypes of mulberry (Morus alba),” International Journal of Food Sciences and Nutrition, vol. 57, no. 5-6, pp. 305–313, 2006. View at Publisher · View at Google Scholar · View at Scopus
  30. O. Juajun, L. Vanhanen, C. Sangketkit, and G. Savage, “Effect of cooking on the oxalate content of selected Thai vegetables,” Food and Nutrition Sciences, vol. 3, no. 12, pp. 1631–1635, 2012. View at Publisher · View at Google Scholar
  31. P. Dabhade and S. Kotwal, “Effect of combination of Indian medicinal plant extracts on bone oxidative stress in osteoporosis,” Bionano Frontier, vol. 5, no. 2, part 2, pp. 72–76, 2012. View at Google Scholar
  32. A.-L. Liu, Z.-M. Zhang, B.-F. Zhu, Z.-H. Liao, and Z. Liu, “Metallothionein protects bone marrow stromal cells against hydrogen peroxide-induced inhibition of osteoblastic differentiation,” Cell Biology International, vol. 28, no. 12, pp. 905–911, 2004. View at Publisher · View at Google Scholar · View at Scopus
  33. M. Zhang, S. G. Swarts, L. Yin et al., “Antioxidant properties of quercetin,” Advances in Experimental Medicine and Biology, vol. 701, pp. 283–289, 2011. View at Publisher · View at Google Scholar · View at Scopus
  34. H. Derakhshanian, M. Djalali, A. Djazayery et al., “Quercetin prevents experimental glucocorticoid-induced osteoporosis: a comparative study with alendronate,” Canadian Journal of Physiology and Pharmacology, vol. 91, no. 5, pp. 380–385, 2013. View at Publisher · View at Google Scholar · View at Scopus
  35. D. J. Hadjidakis and I. I. Androulakis, “Bone remodeling,” Annals of the New York Academy of Sciences, vol. 1092, pp. 385–396, 2006. View at Publisher · View at Google Scholar · View at Scopus