Review Article
The Protective Role of Antioxidants in the Defence against ROS/RNS-Mediated Environmental Pollution
Table 5
Studies demonstrating adverse or insignificant effects of antioxidant treatment after exposure to environmental pollutants.
| Environmental pollutant | Antioxidants displaying adverse or insignificant effects | Study |
| Ozone (O3) | Vitamin E | Hackney et al. (1981) [240] |
| Cigarette smoke | Beta-carotene (synthetic) | Ruano-Ravina et al. (2006) [241] Albanes (1999) [242] Neuhouser et al. (2003) [243] |
| Asbestos | Beta-carotene | van Helden et al. (2009) [244] |
| UVR | Beta-carotene | Stahl et al. (2006) [124] | Vitamin E and beta-carotene (no protective effect) |
McArdle et al. (2004) [245] Wolf et al. (1988) [246] Garmyn et al. (1995) [247] |
| Bipyridinium herbicides (paraquat, diquat and difenzoquat) | Iron and copper | Korbashi et al. (1986) [248] Kohen and Chevion (1985) [249] |
| Polychlorinated dibenzo-para-dioxins (dioxins) and polychlorinated dibenzofurans (furans) | Vitamin E (no protective effect) | Latchoumycandane and Mathur (2002) [250] |
| No extraexposure to environmental pollutants | Green tea catechins (enhanced colon carcinogenesis in rats) | Furukawa et al. (2003) [251] | Melatonin (may exhibit carcinogenic potential) | Sakano et al. (2004) [252] |
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