Nitric Oxide Synthetic Pathway in Patients with Microvascular Angina and Its Relations with Oxidative Stress

Table 2

Biochemical determinations in plasma and RBCs.

	Plasma			RBC
	MVA (𝑛=25)	CAD (𝑛=22)	Ctrl (𝑛=20)	MVA (𝑛=25)	CAD (𝑛=22)	Ctrl (𝑛=20)
Arg	74.22; [69.15--87.08]	82.88; [64.81--95.74]	84.80; [73.13--98.01]	7.57; [5.00--9.53]	8.64; [5.31--10.48]	6.84; [3.86--7.80]
Cit	27.45; [24.21--31.16]	27.61; [20.41--33.83]	26.55; [24.13--30.68]	11.36; [9.58--12.35]	10.48; [8.36--12.11]	8.37; [7.04--10.78]
Orn	47.66; [41.19--54.11]	51.82^#; [48.72--61.68]	40.84; [34.09--46.08]	39.48; [29.52--49.06]	42.59; [36.74--44.90]	33.93; [23.77--43.07]
ADMA	0.51^#; [0.43--0.60]	0.49^#; [0.45--0.59]	0.41; [0.35--0.47]	0.18^#; [0.14--0.27]	0.20^#; [0.15--0.25]	0.15; [0.12--0.20]
SDMA	0.47; [0.42--0.60]	0.54; [0.45--0.63]	0.42; [0.36--0.48]	0.13^##; [0.09--0.16]	0.13^#; [0.12--0.15]	0.10; [0.06--0.11]
MMA	0.12; [0.09--0.13]	0.11; [0.08--0.13]	0.12; [0.10--0.14]	0.13^∗; [0.07--0.18]	0.05; [0.04--0.09]	0.09; [0.05--0.12]
Arg bioavailability	1.06^#; [0.90--1.26]	1.01^#; [0.87--1.22]	1.25; [1.04--1.41]	0.13; [0.11--0.19]	0.16; [0.12--0.19]	0.14; [0.09--0.20]
Orn/Cit ratio	1.74; [1.42--2.21]	1.97^###; [1.69--2.40]	1.48; [1.36--1.71]	3.88^∗; [3.10--4.41]	3.96; [3.51--5.03]	3.92; [3.20--4.32]

Quantitative variables are expressed as median [interquartile interval]. ^∗𝑃<0.05 versus CAD; ^#𝑃<0.05, ^##𝑃<0.01, and ^###𝑃<0.001 versus Ctrl adjusted for age and gender after log-transformation of the data.