Research Article

Bach1 Deficiency and Accompanying Overexpression of Heme Oxygenase-1 Do Not Influence Aging or Tumorigenesis in Mice

Figure 6

Semantic analysis of the genes which were affected by aging in the livers of Bach1-deficient mice. (a) Ten most significantly enriched canonical pathways are listed in significance order (Fisher’s exact test). (b) Heat map visualization of the genes from ten most significantly enriched canonical pathways. (c) GO analysis of the genes from ten most significantly enriched canonical pathways. The GO terms are listed in enrichment significance order (Fisher’s exact test). (d) Heat map visualizations of the genes corresponding to the GO terms monooxygenase activity and oxidoreductase activity in the panel (c). (e) mRNA levels of Alas1 normalized with beta-actin. The results are expressed as mean ± S.D . .
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