Research Article

The Combined Extract of Purple Waxy Corn and Ginger Prevents Cataractogenesis and Retinopathy in Streptozotocin-Diabetic Rats

Table 1

Opacity index of the lens of normal and diabetic rats (DM) which received either vehicle or PWCG at doses of 50, 100, and 200 mg⋅kg−1 BW for 10 weeks (/group). ,  value < 0.01 and 0.001, respectively, compared with control group. , ,  value < 0.05, 0.01, and 0.001 respectively, compared with diabetic rats which received vehicle (DM + vehicle).

Time durationOpacity index of the lens (mean ± SEM)
ControlDM + vehicleDM + PWCG
(50 mg/kg⋅BW−1)
DM + PWCG
(100 mg/kg⋅BW−1)
DM + PWCG
(200 mg/kg⋅BW−1)

Baseline0.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.00
Week 10.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.000.00 ± 0.00
Week 20.00 ± 0.000.06 ± 0.060.00 ± 0.000.00 ± 0.000.00 ± 0.00
Week 30.00 ± 0.000.50 ± 0.16##0.14 ± 0.10*0.50 ± 0.130.22 ± 0.10
Week 40.00 ± 0.001.00 ± 0.20###0.79 ± 0.241.00 ± 0.180.72 ± 0.23
Week 50.00 ± 0.001.81 ± 0.31###1.00 ± 0.21*1.25 ± 0.231.00 ± 0.28*
Week 60.08 ± 0.082.25 ± 0.32###1.50 ± 0.291.50 ± 0.221.11 ± 0.31**
Week 70.17 ± 0.112.50 ± 0.34###1.71 ± 0.291.88 ± 0.291.44 ± 0.41*
Week 80.25 ± 0.133.06 ± 0.23###2.00 ± 0.30*2.19 ± 0.25*1.67 ± 0.40***
Week 90.50 ± 0.153.81 ± 0.10###2.29 ± 0.35***2.38 ± 0.26***1.78 ± 0.39***
Week 100.50 ± 0.154.00 ± 0.00###2.21 ± 0.37***2.63 ± 0.26***1.89 ± 0.40***