Endogenous Ceramide Contributes to the Transcytosis of oxLDL across Endothelial Cells and Promotes Its Subendothelial Retention in Vascular Wall

Figure 4

Fluorescence microscopic analysis of FITC-oxLDL (50 μg/mL) retention in human umbilical venous walls. (a) Representative fluorescence microscopic images of FITC-oxLDL retention in human umbilical venous walls stimulated by PBS or various inhibitors. Scale bars are equal to 300 μm. “Naïve oxLDL” group was incubated with unlabeled oxLDL. (b) Quantification analysis of FITC-oxLDL retention. ^∗𝑃<0.05 versus control, 𝑛=3.

(a)

(b)