Endogenous Ceramide Contributes to the Transcytosis of oxLDL across Endothelial Cells and Promotes Its Subendothelial Retention in Vascular Wall

Figure 6

Expression of proteins related to oxLDL transcytosis in LRs in HUVECs. HUVECs were incubated with 30 μM MYR, 10 μM DES, 30 μM D609, or 10 μM NOE for 12 h and then LRs were isolated and detected with western blot. (a) Representative western blot showing the subcellular localization of the protein marker for LRs, caveolin-1. (b) Representative western blot showing the expression of proteins involved in oxLDL transcytosis in LRs, cavin-1 and Lox-1. (c) Quantitative analysis of the protein expression. ^∗𝑃<0.05, ^∗∗𝑃<0.01 versus control, 𝑛=4.

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