Taurine Rescues Cisplatin-Induced Muscle Atrophy In Vitro: A Morphological Study

Table 1

Apoptosis and necrosis percentages in C2C12 myotubes exposed for 24 h to increasing concentration of CisPt in the presence or not of 3-methyladenine (3-MA).

Treatment	Apoptosis; (mean ± SE)	Necrosis; (mean ± SE)
DMSO	1.7±0.2	n.d.
CisPt 10 𝜇M	1.9±0.5	n.d.
CisPt 50 𝜇M	3.1±0.9^∘	n.d.
DMSO + 3-MA	1.9±0.6	n.d.
CisPt 10 𝜇M + 3-MA	31.4±1.6^∗∘	2.4±0.8^∗∘
CisPt 50 𝜇M + 3-MA	37.5±4.3^∗∘	5.1±0.2^∗∘

n.d.: not detected; ^∗𝑃≤0.05 statistically significant with respect to CisPt 50 alone treatment; ^∘𝑃≤0.05 statistically significant with respect to DMSO.