Oxidative Stress Induced in Nurses by Exposure to Preparation and Handling of Antineoplastic Drugs in Mexican Hospitals: A Multicentric Study

Table 2

Oxidative stress markers in control and occupationally exposed nurses groups.

Biochemical marker	Control group	Occupationally exposed group	𝑃 value
LPX (𝜇mol MDA/mg Hb)	1.9±0.05	4.8±0.14^∗	𝑃<0.05
PCC (𝜇mol carbonyls/mg Hb)	1.6±0.07	3.5±0.08^∗	𝑃<0.05
SOD (UI/mg Hb)	4.5±0.09	7.9±0.07^∗	𝑃<0.05
CAT (mM H2O2/mg Hb)	1.2±0.02	2.0±0.05^∗	𝑃<0.05
GPx (mM NADPH/mg Hb)	5.1±0.06	18.75±0.09^∗	𝑃<0.05

Data were expressed as the mean ± SD. Values significantly different compared to control group were indicated with ^∗(𝑃<0.05). LPX: lipid peroxidation level; MDA: malondialdehyde; Hb: hemoglobin; PCC: protein carbonyl content; SOD: superoxide dismutase activity; CAT: catalase activity; GPx: glutathione peroxidase activity.