Salidroside Stimulates Mitochondrial Biogenesis and Protects against H₂O₂-Induced Endothelial Dysfunction

Figure 1

Protective effects of SAL on H₂O₂-induced cytotoxicity in HUVECs. (a) HUVECs were exposed to various concentrations of H₂O₂ for 4 h. (b) Cells were exposed to various concentrations of SAL for 24 h. (c) HUVECs were pretreated with SAL or vehicle for 20 h and then exposed to H₂O₂ (100 μM) for 4 h. Cell viability was detected by CCK-8. Cell viability in untreated cells was assigned the value of 1. ^∗𝑃<0.05, ^∗∗𝑃<0.01 versus control; ^†𝑃<0.05 versus H₂O₂, 𝑛 = 3–5.

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