Salidroside Stimulates Mitochondrial Biogenesis and Protects against H₂O₂-Induced Endothelial Dysfunction

Figure 6

Effects of SAL on mitochondrial biogenesis. (a) Mitochondria mass was quantified using Mito Tracker Green. Scale bars = 50 μm. The fluorescence in untreated cells was assigned the value of 1. ^∗𝑃<0.05 versus control, 𝑛=4. HUVECs were treated with SAL (1, 10 μM) for 24 h, and the total protein was extracted; the lysates were analyzed by western blot. (b) Representative immunoblots. (c) Summary histograms of the relative density of PGC-1α and TFAM normalized to β-actin. The expression in untreated cells was assigned the value of 1. ^∗𝑃<0.05 versus control, 𝑛=5.

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