Circulating Levels of Sirtuin 4, a Potential Marker of Oxidative Metabolism, Related to Coronary Artery Disease in Obese Patients Suffering from NAFLD, with Normal or Slightly Increased Liver Enzymes

Table 2

Independent variables predicting SIRT4 levels.

	Coefficient	Std. error	95% CI	𝑡	𝑅^2	𝑃
WC; females	−0.98	0.34	−1.6 to −0.30	−2.9	0.09	0.0050
WC; males	−1.6	0.59	−2.7 to −0.42	−2.7	0.011	0.0086
HDL; females	0.7	0.26	0.23 to 1.25	2.9	0.09	0.0053
HDL; males	1.13	0.28	0.58 to 1.7	4.1	0.21	0.001
HS	−0.049	0.013	−0.077 to −0.02	−3.5	0.08	0.0005
Age	−0.94	0.23	−1.4 to −0.48	4.0	0.10	0.0001
cIMT	−0.0016	0.0006	−0.003 to −0.0004	−2.7	0.05	0.0075
W-H ratio	− 0.004	0.0011	0.006 to 0.002	−3.2	0.09	0.003
VAT at US; males	−0.19	0.08	−0.36 to −0.03	−2.4	0.08	0.02
HeS	−0.026	0.01	−0.048 to −0.004	−2.3	0.04	0.02
BMI	−0.49	0.15	−0.80 to −0.19	−3.2	0.07	0.0016

Body mass index (BMI); waist circumference (WC); resting metabolic rate/free fat mass (RMR/FFM); visceral adipose tissue (VAT); high density lipoprotein cholesterol (HDL); common carotid intima-media thickness (cIMT); waist-to-hip (W-H); hepatic steatosis (HS) score; ultrasound (US); Heckmatt score (Hes).