Research Article

Olive (Olea europaea) Leaf Extract Induces Apoptosis and Monocyte/Macrophage Differentiation in Human Chronic Myelogenous Leukemia K562 Cells: Insight into the Underlying Mechanism

Figure 3

Effect of Chemlali Olive Leaf Extract (COLE) on the cell number and viability of K562 cells. (a) Number of viable cells after treatment with COLE after incubation up to 6 days. (b) Percentage of viability in K562 cells treated with COLE. K562 cells were treated at a final concentration of 50, 100, and 150 μg/mL of COLE and incubated for different periods. Cell number and cell viability were measured by flow cytometry. Control represents cells treated with 0.3% ethanol in medium. Results are represented as the mean ± SD of three independent experiments. *, **: significantly different from the control ( and , resp.).
927619.fig.003a
(a)
927619.fig.003b
(b)