Ovarian Aging-Like Phenotype in the Hyperandrogenism-Induced Murine Model of Polycystic Ovary

Table 3

Comparative assessment of OS and inflammation parameters in blood and ovary of PCO and control groups.

	Control	PCO
Blood LPO (μmol/mL)	4.09±0.32	12.72±0.27^∗∗∗
Ovary LPO (μmol/mL)	3.45±0.28	14.21±0.56^∗∗∗
Blood ROS (nmol/min/mg protein)	0.78±0.18	2.76±0.32^∗∗∗
Ovary ROS (nmol/min/mg protein)	0.04±0.00	0.14±0.01^∗∗∗
Blood TAC (nmol/L per mg protein)	209.52±4.66	116.60±4.21^∗∗∗
Ovary TAC (u/mg)	7.68±0.49	2.91±0.16^∗∗∗
Serum TNF-α (pg/mg protein)	41.90±0.42	68.20±2.57^∗∗∗
MMP-2 (ng/mg protein)	23.90±6.00	65.50±15.57^∗∗∗
Insulin (ng/mL)	0.32±0.05	1.10±0.14^∗∗∗

∗represents a significant difference between control and PCO group.
The symbols represent statistical significance: *𝑃<0.05, **𝑃<0.01, and ***𝑃<0.001.