Effects of Downregulation of MicroRNA-181a on H₂O₂-Induced H9c2 Cell Apoptosis via the Mitochondrial Apoptotic Pathway

Figure 1

Cell viability and protein expression changes in H₂O₂-treated H9c2 cells. (a) H9c2 cells were treated with various doses of H₂O₂ for 2 h and assessed for cell viability. ^∗𝑃<0.05 versus control (CTL); ^∗∗𝑃<0.01 versus control (CTL); the values represent the mean ± SEM, 𝑛=5. (b) Gpx1 and β-actin protein levels were detected by western blotting after the treatment of H9c2 cells with different concentrations of H₂O₂ for 2 h. ^∗𝑃<0.05 versus control (CTL); ^∗∗𝑃<0.01 versus control (CTL); the values represent the mean ± SEM, 𝑛=3.

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