Urinary Excretion of Neutrophil Gelatinase-Associated Lipocalin in Diabetic Rats
Table 2
Evaluation of oxidative stress at 7 days.
Control
Diabetic
Diabetic-insulin treated
CAT (U/mL)
1780 ± 294.7
1459 ± 109.6
1791 ± 205.3
GPx (U/mL)
106.2 ± 1.19
116.1 ± 2.46
109.1 ± 3.17
SOD (U/mL)
651.8 ± 9.52
662.0 ± 10.96
683.6 ± 6.79
Carbonyl content in Ctx (nmol/mg protein)
1.75 ± 0.90
4.36 ± 1.67
2.72 ± 0.25
Carbonyl content in Med (nmol/mg protein)
13.73 ± 3.01
7.91 ± 2.28
7.26 ± 2.89
4-HNE content in Ctx (nmol/mg protein)
0.22 ± 0.19
0.89 ± 0.22
0.83 ± 0.27
4-HNE content in Med (nmol/mg protein)
0.41 ± 0.25
1.09 ± 0.28
1.04 ± 0.30
CAT: catalase, GPx: glutathione peroxidase, SOD: superoxide dismutase, Ctx: renal cortex, Med: renal medulla, and 4-HNE: 4-hydroxynonenal. Data are mean SEM of 8 animals in each group. versus control; versus diabetic.