Polyol Pathway Exacerbated Ischemia/Reperfusion-Induced Injury in Steatotic Liver

Figure 4

AR-overexpression promoted the activation of caspase 3 in steatosis hepatocytes after H/R. (a)–(c) In western blot, Bcl-2 and Bcl-2/Bax ratio were markedly suppressed by AR overexpressing; whereas Bax and cleaved caspase 3 were enhanced (for each condition, data are expressed as mean ± SEM and analyzed by unpaired Student’s 𝑡-test; 𝑛=5, ^∗𝑃<0.01; ^∗∗𝑃<0.05).

(a)

(b)

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