Choline and Cystine Deficient Diets in Animal Models with Hepatocellular Injury: Evaluation of Oxidative Stress and Expression of RAGE, TNF-α, and IL-1β

Figure 1

Representative photomicrographs of hematoxylin and eosin staining of liver sections. St (1a) (200x): arrow indicating periportal zone with disorganized hepatocyte cords; St (1b) (300x): hepatic steatosis, arrow indicating fat accumulation in hepatic intracellular vacuole; CD (2a) (200x): arrow indicating hepatic cord disorganisation around centrilobular zone, hepatic steatosis, and signals suggestive of fibrosis; CD (2b) (400x): arrows indicating ballooning degeneration of hepatocytes and macro and microvesicular steatosis; CCD (3a) (200x): arrow indicating hepatic cord disorganisation, nucleus with increased size, and microvesicular steatosis; St (3b) (300x): right arrow indicating nucleus with increased size and arrow nuclear breakdown, Mallory corpuscles.