TSG (2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside) from the Chinese Herb Polygonum multiflorum Increases Life Span and Stress Resistance of Caenorhabditis elegans

Figure 6

Prolongation of life span by treatment with TSG. (a) Pretreatment with 100 μM of TSG, resveratrol, and quercetin reduced the accumulation of the ageing marker lipofuscin (mean values ± SEM, , versus control value, Student’s -test). 20 animals per group and experiment were analysed. (b) All compounds (100 μM) induced a prolongevity effect during the complete adult life (Kaplan-Meier survival analysis of three independent experiments with at least 30 animals per group/experiment; survival data are summarised in Table 2).

(a)

(b)