Research Article

TSG (2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside) from the Chinese Herb Polygonum multiflorum Increases Life Span and Stress Resistance of Caenorhabditis elegans

Figure 7

The TSG-mediated prolongation of life span is independent of DAF-16. Treatment with the compounds (100 μM) during the complete adult life induced a prolongevity effect in the daf-16 loss-of-function mutant strain CF1038 (Kaplan-Meier survival analysis of two independent experiments with at least 30 animals per group/experiment; survival data are summarised in Table 2).