Review Article

Advances in the Pathogenesis of Cardiorenal Syndrome Type 3

Table 1

Cardiorenal syndrome (CRS) classification.

Acute cardiorenal syndromeCRS type 1Abrupt worsening of cardiac function leading to acute kidney injury, for example, acute heart failure; cardiac surgery; acute coronary syndrome; contrast-induced nephropathy

Chronic cardiorenal syndromeCRS type 2Chronic abnormalities of cardiac function causing chronic kidney disease, for example, Ischemic Heart Disease; Hypertension; chronic heart disease; chronic heart failure

Acute renocardiac syndromeCRS type 3Abrupt worsening of renal function leading to acute cardiac dysfunction
Acute pulmonary edema in acute kidney injury; arrhythmia

Chronic renocardiac syndromeCRS type 4Chronic kidney disease leading to chronic cardiac dysfunction, for example, left ventricular hypertrophy; adverse cardiovascular events in chronic kidney disease

Secondary cardiorenal syndromeCRS type 5Systemic disorders causing both cardiac and renal dysfunction, for example, sepsis; systemic lupus erythematosus; diabetes mellitus