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Oxidative Medicine and Cellular Longevity
Volume 2015, Article ID 150829, 10 pages
Research Article

Tocotrienol Rich Palm Oil Extract Is More Effective Than Pure Tocotrienols at Improving Endothelium-Dependent Relaxation in the Presence of Oxidative Stress

School of Medical Sciences, Health Innovations Research Institute, RMIT University, Bundoora, VIC 3083, Australia

Received 5 January 2015; Revised 24 April 2015; Accepted 24 April 2015

Academic Editor: Giuseppe Cirillo

Copyright © 2015 Saher F. Ali and Owen L. Woodman. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [11 citations]

The following is the list of published articles that have cited the current article.

  • Francesca Santilli, Damiano D'Ardes, and Giovanni Davì, “Oxidative stress in chronic vascular disease: From prediction to prevention,” Vascular Pharmacology, 2015. View at Publisher · View at Google Scholar
  • Jaafar, Wan Ngah, Suzana Makpol, Durani, Tan, Tajul Arifin, and Mohd Yusof, “Targeting genes in insulin-associated signalling pathway, DNA damage, cell proliferation and cell differentiation pathways by tocotrienol-rich fraction in preventing cellular senescence of human diploid fibroblasts,” Clinica Terapeutica, vol. 166, no. 6, pp. 365–373, 2015. View at Publisher · View at Google Scholar
  • Wang Xiye, Shan Xiaotong, Wang Yilin, Li Dan, Zhao Ming, and Xu Liang, “Mechanism of Salvia Miltiorrhiza on the Improvement of Myocardial Function in Patients with Dilated Cardiomyopathy,” Chemical Journal Of Chinese Universities-Chinese, vol. 37, no. 5, pp. 844–851, 2016. View at Publisher · View at Google Scholar
  • Saher F. Ali, Jason C. D. Nguyen, Trisha A. Jenkins, and Owen L. Woodman, “Tocotrienol-Rich Tocomin Attenuates Oxidative Stress and Improves Endothelium-Dependent Relaxation in Aortae from Rats Fed a High-Fat Western Diet,” Frontiers in Cardiovascular Medicine, vol. 3, 2016. View at Publisher · View at Google Scholar
  • London Allen, Latha Ramalingam, Kalhara Menikdiwela, Shane Scoggin, Chwan-Li Shen, Michael D. Tomison, Gurvinder Kaur, Jannette M. Dufour, Eunhee Chung, Nishan S. Kalupahana, and Naima Moustaid-Moussa, “Effects of Delta-Tocotrienol on Obesity-Related Adipocyte Hypertrophy, Inflammation, and Hepatic Steatosis in High Fat Fed Mice,” The Journal of Nutritional Biochemistry, 2017. View at Publisher · View at Google Scholar
  • Daniel U. Owu, Etah E. Nkanu, and Eme E. Osim, “Altered Potassium Ion Channel Function as a Possible Mechanism of Increased Blood Pressure in Rats Fed Thermally Oxidized Palm Oil Diets,” Journal of Dietary Supplements, pp. 1–14, 2017. View at Publisher · View at Google Scholar
  • Faizul Jaafar, Asmaa Abdullah, and Suzana Makpol, “Cellular Uptake and Bioavailability of Tocotrienol-Rich Fraction in SIRT1-Inhibited Human Diploid Fibroblasts,” Scientific Reports, vol. 8, no. 1, 2018. View at Publisher · View at Google Scholar
  • Lina Wati Durani, Hamizah Shahirah Hamezah, Nor Faeizah Ibrahim, Daijiro Yanagisawa, Muhammad Luqman Nasaruddin, Masaki Mori, Kamalrul Azlan Azizan, Hanafi Ahmad Damanhuri, Suzana Makpol, Wan Zurinah Wan Ngah, and Ikuo Tooyama, “Tocotrienol-Rich Fraction of Palm Oil Improves Behavioral Impairments and Regulates Metabolic Pathways in AβPP/PS1 Mice,” Journal of Alzheimer's Disease, vol. 64, no. 1, pp. 249–267, 2018. View at Publisher · View at Google Scholar
  • Azraul Mumtazah Razak, Shy Cian Khor, Faizul Jaafar, Norwahidah Abdul Karim, and Suzana Makpol, “Targeting myomiRs by tocotrienol-rich fraction to promote myoblast differentiation,” Genes & Nutrition, vol. 13, no. 1, 2018. View at Publisher · View at Google Scholar
  • Nardev Ramanathan, Esther Tan, Li Jun Loh, Boon Seng Soh, and Wei Ney Yap, “Tocotrienol is a cardioprotective agent against ageing-associated cardiovascular disease and its associated morbidities,” Nutrition & Metabolism, vol. 15, no. 1, 2018. View at Publisher · View at Google Scholar
  • Saher F. Ali, and Owen L. Woodman, “Tocomin Restores Endothelium-Dependent Relaxation in the Diabetic Rat Aorta by Increasing NO Bioavailability and Improving the Expression of eNOS,” Frontiers in Physiology, vol. 10, 2019. View at Publisher · View at Google Scholar